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Brain’s Blood Flow Could Change How We Understand and Treat Alzheimer’s

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New USC Viterbi-led study focusing on brain’s vascular dynamics challenges the current prevailing method of dementia diagnosis and treatment. Over seven million Americans are living with Alzheimer’s disease (AD) and the heartbreaking day-to-day battle with the effects of cognitive decline. According to the Alzheimer’s Association, the brain changes that cause the disease actually begin 20 years or more before symptoms start, highlighting the critical need for early and accurate diagnosis. However, current diagnostic tools involve painful spinal taps, expensive scans and cognitive tests that can be limited in their accuracy. New research led by biomedical engineers at USC Viterbi School of Engineering has uncovered the key role the brain’s blood flow dynamics play in AD, offering a simpler, non-invasive diagnostic tool that could reshape decades of conventional thinking about how this debilitating disease is understood and treated. Led by Vasilis Marmarelis, Dean’s Professor in...

Optical genome mapping shows promise in predicting pregnancy loss

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  Data presented at the  Association for Molecular Pathology 2025 Annual Meeting & Expo  has indicated increased odds of  pregnancy loss  following chromosome changes, providing a potential opportunity for predicting pregnancy loss. The studies utilized optical genome mapping to evaluate the structure of genomes and identify abnormalities often missed when using traditional sequencing methods. This provides an opportunity to detect genetic or chromosomal issues linked to approximately 50% of pregnancy loss cases. Key gene disruptions Investigators from Dartmouth–Hitchcock Medical Center evaluated the efficacy of optical genome mapping toward identifying negative chromosomal changes among patients at risk or with a family history of recurrent pregnancy loss. Comparisons were made with prior traditional genetic testing given to these patients, such as karyotyping or chromosomal microarray analysis. There were 238 genes evaluated, all of which were associated w...

New study: Pharmacy education needs planetary health focus to boost environmental action

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  New Monash University  research  has found that while pharmacy students understand pharmacists’ role in planetary health, many struggle to apply these principles in practice or link issues like antimicrobial resistance (AMR) to equity and social justice, signalling a critical gap in healthcare education. Published in UK journal, Innovations in Education and Teaching International, the study evaluated the effectiveness of a co-designed Planetary Health Education (PHE) curriculum delivered to 398 pharmacy students across two of Monash University’s campuses in Australia and Malaysia, with a focus on one of the most urgent human-driven challenges impacting planetary health: AMR. Amongst the student cohort, fewer than 4 per cent of students identified a connection between equity and social justice and planetary health, highlighting a gap in understanding that planetary health involves protecting vulnerable populations from disproportionate impacts of environmental degra...

Innovations in Regenerative Medicine: Harnessing the Power of Cells

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Regenerative medicine has emerged as one of the most dynamic fields of modern biomedical research, and stem cells continue to stand at the center of this progress. Their unique capacity for self renewal, lineage commitment, and tissue reconstruction has opened transformative avenues for treating diseases that were previously considered irreversible. This Research Topic focuses on recent innovations that leverage stem cell biology to develop advanced therapeutic strategies, understand disease mechanisms, and engineer complex tissue systems. The field has rapidly expanded beyond traditional stem cell transplantation, integrating cutting edge technologies such as induced pluripotent stem cells, single cell omics, bioengineering platforms, and organoid systems. These innovations offer unprecedented insight into human development, cell fate decisions, and tissue level repair. Stem cell derived models allow researchers to recreate cellular environments that closely resemble human physiology...

Strange Anomalies In Earth’s Molten Beginnings And Its Unique Habitability

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  The illustration shows a cutaway revealing the interior of early Earth with a hot, melted layer above the boundary between the core and mantle. Scientists think some material from the core leaked into this molten layer and mixed in. Over time, that mixing helped create the uneven structure of Earth’s mantle that we see today. Illustration by Yoshinori Miyazaki A Rutgers researcher and collaborators link strange anomalies to Earth’s molten beginnings – and its unique habitability. For decades, scientists have been baffled by two enormous, enigmatic structures buried deep inside Earth with features so vast and unusual that they defy conventional models of planetary evolution. Now, a study published in Nature Geoscience by Rutgers geodynamicist Yoshinori Miyazaki in combination with collaborators offers a striking new explanation for these anomalies and their role in shaping Earth’s ability to support life. The structures, known as large low-shear-velocity provinces and ultra-low-ve...

VMD launches new vaccine supply strategy

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  A new five-year plan is set to be drawn up in a move that officials hope will help to create more resilient supply lines. A new strategy, intended to improve the availability of veterinary vaccines in the UK, has been unveiled by the VMD today (11 September). The document, billed as a statement of intent, envisages the development of a multi-stakeholder, five-year action plan within the next 12 months and calls for a move away from current “just-in-time” supply models. Biosecurity minister Baroness Hayman said: “We need to transition towards a more resilient, just-in-case approach, one that prioritises preparedness to mitigate potential impacts on both animal and human health.” Strategic themes  Common solutions The document sets out four strategic themes – improving supply and uptake, supporting innovation, reviewing the manufacturing landscape and working in partnership – plus 14 associated workstreams. Themes highlighted include addressing knowledge gaps, identifying and ...

Escherichia coli (E. coli) is a Gram-negative, facultative anaerobic bacterium commonly found in the lower intestine of warm-blooded animals

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While most strains are harmless and form an essential part of the normal gut flora, certain serotypes—most notably O157:H7—are capable of causing severe foodborne illness. Beneficial strains contribute to host health by producing vitamin K2 and helping prevent colonization by pathogenic organisms. Due to its ability to survive temporarily outside the body, E. coli also serves as a key indicator organism for fecal contamination in environmental and water quality testing. E. coli is one of the most widely studied model organisms in microbiology and biotechnology. Its simple genetics, rapid growth, and adaptability to varied substrates have made it a cornerstone of molecular biology research. Optimal growth occurs at 37°C, though laboratory strains can tolerate higher temperatures. The bacterium can use a range of metabolic pathways, including mixed-acid fermentation under anaerobic conditions and aerobic or anaerobic respiration using diverse redox pairs. Some strains possess peritrichou...