Experimental mRNA Vaccine Hints at Potential Against Glioblastoma #sciencefather #Researchawards#Brai..
Although immunotherapy is now a mainstay treatment for many cancers, it has yet to break through as a treatment for brain cancer, including the most common type, glioblastoma. But recent results from several small clinical trials have hinted at the possibility of reversing this trend. Among them are findings from a very small trial testing a cancer treatment vaccine developed by researchers at the University of Florida. Like two of the approved COVID vaccines and some other experimental cancer vaccines, this one uses genetic material called mRNA that is loaded into fat-coated nanoparticles. But it also has a unique design aspect compared with these other vaccines: the nanoparticles have layers of fat inside, making it possible to layer each one with large numbers of mRNA. In a study published May 1 in Cell , the researchers reported that the vaccine was effective in pet dogs with naturally occurring brain cancers, allowing them t...
