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Showing posts from February, 2025

High-risk genetic changes with myeloma tied to poorer outcomes

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  Specific abnormalities in cancer cells known to cause more aggressive disease The presence of more than one high-risk genetic abnormality is associated with dramatically more aggressive multiple myeloma, a study reported. Its findings highlight the importance of testing myeloma patients for these genetic abnormalities, helping to better understand their disease’s potential course and guiding treatment decisions, the researchers wrote. “The results of this study have enabled us to more accurately classify the aggressiveness of an individual patient’s cancer,” Martin Kaiser, MD, the study’s lead author and a professor of molecular hematology at The Institute of Cancer Research in the U.K., said in an institute news story. “We would like all myeloma patients to be able to access the newer diagnostic tests which enable clinicians to group individual patients based on their risk profile and provide treatment that is tailored to their needs.” The study, “Co-Occurrence of Cyto...

Cognitive behavioral therapy improves brain circuits to relieve depression: Study

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  The study shows that cognitive behavioral therapy can reduce depression with emphasised problem solving. The findings add to evidence that choosing treatments based on the neurological underpinnings of a patient's depression -- which vary among people -- increases the odds of success.(Unsplash) One of the most popular therapies for  depression  is cognitive behavioural therapy, which can help people learn coping mechanisms for common problems, reinforce positive actions, and challenge negative thinking. But can thinking and acting differently result in long-lasting brain changes? According to recent research from Stanford Medicine, researchers found that it can. If the appropriate patients are matched with a therapy. A third of patients in a study with people who had both depression and obesity--a combination that is challenging to treat--saw a reduction in depression thanks to cognitive behavioral therapy that emphasized problem solving. Additionally, adaptive modifica...

Wyss researchers develop new minimally invasive imaging system for neurosurgery

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  Researchers from the  Wyss Center  published a new paper highlighting a cutting-edge, minimally invasive optical coherence tomography (OCT) system for neurosurgery. According to the Wyss Center, the work presents a novel, forward-viewing, common-path OCT system operating at 1310 nm. It offers real-time, high-resolution imaging capabilities crucial for neurosurgical applications. The system can visualize neuroanatomy and blood flow with detail, enhancing the precision of surgeries like deep brain stimulation (DBS) implantation, brain biopsies and tumor resections, according to Wyss. This technology could address current neurosurgical limitations in four ways, the Wyss Center said. First, its minimally invasive design features a compact, forward-viewing endoscope for compatibility with existing neurosurgical tools. This minimizes invasiveness while enhancing surgical accuracy. Second, real-time tissue and blood vessel visualization enables surgeons to identify and avoid b...

From action representation to action execution: exploring the links between cognitive and biomechanical levels of motor control

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Along with superior performance, research indicates that expertise is associated with a number of mediating cognitive adaptations. To this extent, extensive practice is associated with the development of general and task-specific mental representations, which play an important role in the organization and control of action. Recently, new experimental methods have been developed, which allow for investigating the organization and structure of these representations, along with the functional structure of the movement kinematics. In the current article, we present a new approach for examining the overlap between skill representations and motor output. In doing so, we first present an architecture model, which addresses links between biomechanical and cognitive levels of motor control. Next, we review the state of the art in assessing memory structures underlying complex action. Following we present a new spatio-temporal decomposition method for illuminating the functional structure of mov...

Long COVID and the brain: Global study links infection to memory loss, higher dementia risk in seniors

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  Five years after the height of the SARS-CoV-2 (COVID-19) pandemic, scientists are beginning to unveil the infection’s potential long-term effects on the brain. We now know that following an acute COVID-19 infection, between 10% and 35% of people suffer from lingering effects called long COVID. For some people, these effects can be mild and short-lived, but for others, there may be lasting issues that may trigger a chain reaction of cognitive impairment. Long COVID is a condition following an acute infection of COVID-19 with symptoms lasting a few weeks to several months. Its effects vary from person to person and there are more than 200 reported symptoms. Common symptoms include extreme fatigue, memory problems or “brain fog,” lightheadedness and smell or taste impairment. Along with these symptoms, scientists conjectured that other long COVID effects might impact older people differently. To better understand the connection between long COVID, potential cognitive impairment and ...

The empathy and stress mindset of healthcare workers: the chain mediating roles of self-disclosure and social support

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  The hospital is a workplace full of stressful events for healthcare workers (HCWs) due to unpredictable changes in their daily routines. Perceptions of stressful events (stress mindset) have a significant impact on an individual’s health and well-being. However, few studies have reported the factors and potential counter mechanisms influencing these perceptions. This study aimed to evaluate the relationship between empathy, self-disclosure, social support, and stress mindset of HCWs, and to explore the mechanism of empathy on stress mindset. Five hundred and eight HCWs (35.2% men and 64.8% women) completed the Interpersonal Reactivity Index (IRI), the Distress Disclosure Index (DDI), the Social Support Rating Scale (SSRS), the Stress Mindset Measure (SMM), and demographic questionnaires online in China. The results showed that empathy was positively linked with stress mindset and positively correlated with self-disclosure and social support. In the multiple mediating model, self-...

How chronic stress warps decision-making

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  Nerve-cell ‘highways’ identified in mice suggest that stress pushes the brain towards rigid habit and away from thoughtful choices. Scientists have found two ‘dials’ in the brain that help to explain how  chronic stress  hijacks decision-making 1 . The discovery is based on experiments in mice and will therefore need to be confirmed in humans. But it shows that prolonged stress dials back deliberate decision-making while also boosting an ‘autopilot’ mode in the brain that favours rigid, habitual behaviours. It’s long been known that humans who face chronic stress are prone to resort to a habit, such as smoking a cigarette or eating junk food, rather than make a well-thought-out decision. The work, reported today in  Nature , uncovers a biological mechanism for how stress puts its finger on the scale in favour of routine, scientists say. “It’s really a major achievement,” says Kyle Smith, a neuroscientist at Dartmouth University in Hanover, New Hampsh...

Human Computer Interaction

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Human  Computer Interaction is a place where the user can search for any information they need. The interaction between human and  computer is done to fulfill their works in the user-friendly interface. This program used for many platforms to complete their work with the simple and innovative manner with 100% result. A human can implement any projects either in marketing growth or in cropping filed no matter about the fields. A system is used for everything in the world at any time any place to fulfill your goal without any restrictions. Of course, a computer will also use to entertain the human with multimedia including movies, programs, events, social media, etc. and many more. Computer simplified with many technologies, developments, tools, designed with attractive features day-by-day to make user easy to use with a simple guide. And one more thing people should know that a computer may do bad for the users that depend on the users to make use of it.   What is HCI (Hum...