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Showing posts from December, 2025

Analog Circuits: Simulating Heartbeats with Reaction-Diffusion Magic!

Analog circuits simulating heartbeats with reaction–diffusion magic model how electrical waves propagate through cardiac tissue. By combining nonlinear components, timing networks, and diffusion-like coupling, these circuits recreate rhythmic pulses, arrhythmias, and recovery phases, enabling researchers to study bio-inspired computing, medical device testing, and realistic cardiac signal generation.  Website: cognitivescientist.org  Nomination now: https://cognitivescientist.org/award-nomination/?ecategory=Awards&rcategory=Awardee  Contact: cognitivescientist.org  Twitter: https://x.com/home  Blogger: https://www.blogger.com/  facebook: https://www.facebook.com/  Instagram: https://www.instagram.com/  Pinterest: https://in.pinterest.com/cognitivescientist/  #cognitive #researchscientist  #researcher  #analogcircuits  #heartbeatmodeling  #reactiondiffusion  #cardiacelectronics  #bioinspiredcircuits  #ne...

Scientists reverse Alzheimer’s in mice and restore memory

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  Researchers found that Alzheimer’s is driven in part by a collapse in the brain’s energy balance—and fixing it can reverse the disease in animal models. Even mice with advanced Alzheimer’s regained brain function and memory, suggesting recovery may be possible. Credit: AI/ScienceDaily.com A study reveals that restoring the brain's energy balance may not just slow Alzheimer's -- but actually reverse it. For more than a century, Alzheimer's disease has been widely viewed as permanent and untreatable once it begins. As a result, most research has focused on preventing the disease or slowing its progression rather than attempting to reverse it . By studying multiple mouse models of Alzheimer's alongside human Alzheimer's brain tissue, researchers identified a critical biological problem at the center of the disease. They found that the brain's inability to maintain healthy levels of a vital cellular energy molecule called NAD+ plays a major role in driving Alzheim...

Brain’s Blood Flow Could Change How We Understand and Treat Alzheimer’s

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New USC Viterbi-led study focusing on brain’s vascular dynamics challenges the current prevailing method of dementia diagnosis and treatment. Over seven million Americans are living with Alzheimer’s disease (AD) and the heartbreaking day-to-day battle with the effects of cognitive decline. According to the Alzheimer’s Association, the brain changes that cause the disease actually begin 20 years or more before symptoms start, highlighting the critical need for early and accurate diagnosis. However, current diagnostic tools involve painful spinal taps, expensive scans and cognitive tests that can be limited in their accuracy. New research led by biomedical engineers at USC Viterbi School of Engineering has uncovered the key role the brain’s blood flow dynamics play in AD, offering a simpler, non-invasive diagnostic tool that could reshape decades of conventional thinking about how this debilitating disease is understood and treated. Led by Vasilis Marmarelis, Dean’s Professor in...

Optical genome mapping shows promise in predicting pregnancy loss

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  Data presented at the  Association for Molecular Pathology 2025 Annual Meeting & Expo  has indicated increased odds of  pregnancy loss  following chromosome changes, providing a potential opportunity for predicting pregnancy loss. The studies utilized optical genome mapping to evaluate the structure of genomes and identify abnormalities often missed when using traditional sequencing methods. This provides an opportunity to detect genetic or chromosomal issues linked to approximately 50% of pregnancy loss cases. Key gene disruptions Investigators from Dartmouth–Hitchcock Medical Center evaluated the efficacy of optical genome mapping toward identifying negative chromosomal changes among patients at risk or with a family history of recurrent pregnancy loss. Comparisons were made with prior traditional genetic testing given to these patients, such as karyotyping or chromosomal microarray analysis. There were 238 genes evaluated, all of which were associated w...